Jakmip1 Gene Summary [Rat]

Predicted to enable GABA receptor binding activity; RNA binding activity; and kinesin binding activity. Predicted to be involved in cognition. Located in microtubule cytoskeleton. Orthologous to human JAKMIP1 (janus kinase and microtubule interacting protein 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Jakmip1
Official Name
janus kinase and microtubule interacting protein 1 [Source:RGD Symbol;Acc:1562401]
Ensembl ID
ENSRNOG00000004998
Bio databases IDs NCBI: 305434 Ensembl: ENSRNOG00000004998
Aliases janus kinase and microtubule interacting protein 1
Synonyms 5830437M04Rik, C330021K24Rik, Gababrbp, JAMIP1, janus kinase and microtubule interacting protein 1, MARLIN1, Mgi:1923321
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Jakmip1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • chromosome segregation protein SMC, common bacterial type
  • RecF/RecN/SMC N terminal domain
  • chromosome segregation protein SMC, primarily archaeal type
  • JAKMIP CC3 domain
  • coiled-coil domain
  • protein binding
  • receptor binding
  • kinesin binding
  • RNA binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Crohn disease
  • diabetic nephropathy
  • coronary artery disease
  • Smith-Magenis syndrome-like disorder
regulated by
regulates
role in cell
  • organization

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • soluble fraction
  • detergent-insoluble fractions
  • membrane fraction
  • microtubule cytoskeleton
  • cellular membrane
  • microtubules
  • granules
  • granular components
  • neurites
  • perikaryon

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Jakmip1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cognition
  • protein transport

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • membrane
  • microtubule

Molecular Function

What the gene product does at the molecular level
  • RNA binding
  • protein binding
  • GABA receptor binding
  • kinase binding
  • microtubule binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.