Trim12a Gene Summary [Mouse]
Predicted to enable several functions, including protein homodimerization activity; transcription coactivator activity; and ubiquitin protein ligase activity. Predicted to be involved in several processes, including defense response to other organism; positive regulation of NF-kappaB transcription factor activity; and regulation of signal transduction. Located in cytoplasm. Is expressed in bladder; central nervous system; and testis. [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Processed Transcript |
| Official Symbol | Trim12a |
| Official Name | tripartite motif-containing 12A [Source:MGI Symbol;Acc:MGI:1923931] |
| Ensembl ID | ENSMUSG00000066258 |
| Bio databases IDs | |
| Aliases | tripartite motif-containing 12A |
| Synonyms | 2310043C01Rik, Trim12, tripartite motif-containing 12A |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Trim12a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transcription co-activator
- signaling receptor activity
- protein kinase binding
- zinc finger of C3HC4-type, RING
- protein binding activity, bridging
- enzyme
- Ring finger domain
- identical protein binding
- B-box-type zinc finger superfamily
- RING-type zinc-finger
- RING finger (Really Interesting New Gene) domain and U-box domain superfamily
- Ring finger
- ubiquitin-protein transferase activity
- protein homodimerization
- B-box zinc finger
- Zinc finger, C3HC4 type (RING finger)
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- omegasome
- cytoplasmic mRNA processing body