B3galt4 Gene Summary [Mouse]
Predicted to enable N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity. Predicted to be involved in ganglioside biosynthetic process and protein O-linked glycosylation. Predicted to be active in Golgi membrane. Is expressed in several structures, including brain; genitourinary system; heart; hemolymphoid system gland; and liver. Orthologous to human B3GALT4 (beta-1,3-galactosyltransferase 4). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | B3galt4 |
| Official Name | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 [Source:MGI Symbol;Acc:MGI:1859517] |
| Ensembl ID | ENSMUSG00000067370 |
| Bio databases IDs | |
| Aliases | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| Synonyms | Beta-1,3-galactosyltransferase 4, BETA3GALT4, GALT2, GALT4, LOC100045158, UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4, UDP-Gal:betaGlcNAc β 1,3-galactosyltransferase, polypeptide 4, β-1,3-galactosyltransferase 4 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse B3galt4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- UDP-galactose beta-N-acetylglucosamine beta-1,3-galactosyltransferase
- galactosyltransferase
- ganglioside galactosyltransferase
- enzyme
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- non-small cell lung carcinoma
- non-small cell lung cancer
- organismal death
- systemic juvenile idiopathic arthritis
- intoxication
- Huntington disease
regulates
- glycosphingolipid
- ganglioside GM1
- oligosaccharide
- ganglioside
role in cell
- accumulation
- progression
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Golgi Apparatus
- Golgi membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse B3galt4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein O-linked glycosylation
- oligosaccharide biosynthetic process
- glycosphingolipid biosynthetic process
- ganglioside biosynthetic process
Cellular Component
Where in the cell the gene product is active
- Golgi membrane
Molecular Function
What the gene product does at the molecular level
- ganglioside galactosyltransferase activity
- UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity