Cnpy3 Gene Summary [Mouse]

This gene encodes a member of the canopy family of proteins. The encoded protein may play a role in the maturation of toll-like receptors. Homozygous knockout mice for this gene show reduced cell surface expression of toll-like receptors and an impaired immune response including reduced production of cytokines in a mouse model of sepsis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

Details

Type
Protein Coding
Official Symbol
Cnpy3
Official Name
canopy FGF signaling regulator 3 [Source:MGI Symbol;Acc:MGI:1919279]
Ensembl ID
ENSMUSG00000023973
Bio databases IDs NCBI: 72029 Ensembl: ENSMUSG00000023973
Aliases canopy FGF signaling regulator 3
Synonyms 1600025D17RIK, 2410050O22Rik, AI413153, CAG4A, canopy FGF signaling regulator 3, DEE60, EIEE60, ERDA5, LOC683377, PRAT4A, TNRC5
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cnpy3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • TLR4 regulator and MIR-interacting MSAP
  • receptor binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • early infantile epileptic encephalopathy type 60
  • growth failure
regulated by
  • GnRH analog
regulates
role in cell
  • expression in
  • response
  • function

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Endoplasmic Reticulum
  • endoplasmic reticulum lumen

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Cnpy3 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • innate immune response

Cellular Component

Where in the cell the gene product is active
  • endoplasmic reticulum lumen

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • receptor binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.