Col28a1 Gene Summary [Mouse]
Predicted to enable heparin binding activity. Predicted to be an extracellular matrix structural constituent conferring tensile strength. Predicted to be involved in extracellular matrix organization. Located in basement membrane. Is expressed in several structures, including main olfactory bulb; metapodial pad; peripheral nervous system; skeletal muscle; and skin. Orthologous to human COL28A1 (collagen type XXVIII alpha 1 chain). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Col28a1 |
| Official Name | collagen, type XXVIII, alpha 1 [Source:MGI Symbol;Acc:MGI:2685312] |
| Ensembl ID | ENSMUSG00000068794 |
| Bio databases IDs | |
| Aliases | collagen, type XXVIII, alpha 1 |
| Synonyms | COL28, collagen, type XXVIII, alpha 1, collagen type XXVIII alpha 1 chain, collagen, type XXVIII, α 1, collagen type XXVIII α 1 chain, Collagen xxviii, Col xxviii, Gm466, RGD1564680 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Col28a1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Kunitz/Bovine pancreatic trypsin inhibitor (BPTI) domain
- von Willebrand factor (vWF) type A domain
- vWFA
- Collagen triple helix repeat (20 copies)
- von Willebrand factor type A domain
Pathways
Biological processes and signaling networks where the Col28a1 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- endoplasmic reticulum lumen
- basement membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Col28a1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell adhesion
- collagen fibril organization
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum lumen
- extracellular space
- basement membrane
- extracellular region
- collagen type V
Molecular Function
What the gene product does at the molecular level
- serine-type endopeptidase inhibitor activity
- extracellular matrix structural constituent conferring tensile strength
- heparin binding