Cited4 Gene Summary [Mouse]
Enables transcription coactivator activity. Involved in response to estrogen. Acts upstream of or within positive regulation of DNA-templated transcription. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; eye; genitourinary system; hemolymphoid system; and trunk mesenchyme. Orthologous to human CITED4 (Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cited4 |
| Official Name | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 [Source:MGI Symbol;Acc:MGI:1861694] |
| Ensembl ID | ENSMUSG00000070803 |
| Bio databases IDs | |
| Aliases | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 |
| Synonyms | CBP Interacting Transactivator4, Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4, Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4, MRG-2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cited4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transcription regulator
- transcription co-activator
- CITED
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cited4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- response to estrogen stimulus
- positive regulation of transcription, DNA-dependent
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- transcription coactivator activity