Rimbp3 Gene Summary [Mouse]

Predicted to enable benzodiazepine receptor binding activity. Involved in fertilization and spermatid development. Located in nucleus. Colocalizes with manchette. Orthologous to several human genes including RIMBP3 (RIMS binding protein 3). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Rimbp3
Official Name
RIMS binding protein 3 [Source:MGI Symbol;Acc:MGI:2685449]
Ensembl ID
ENSMUSG00000071636
Bio databases IDs NCBI: 239731 Ensembl: ENSMUSG00000071636
Aliases RIMS binding protein 3
Synonyms Gm1759, Gm603, mKIAA1666, RGD1563657, RIM-BP3.1, RIMBP3A, RIM-BP3.A, RIMS binding protein 3
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rimbp3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Domain of unknown function (DUF4515)
  • UDM1_RNF168_RNF169-like
  • FN3
  • Purple acid Phosphatase, N-terminal domain
  • protein binding
  • Fibronectin type 3 domain
  • Flagellar protein FliT
  • Src Homology 3 domain superfamily

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • oligozoospermia
regulated by
role in cell
  • formation
  • development
  • arrangement
  • abnormal morphology
  • fertilization
  • detachment

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • manchette
  • Nucleus

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Rimbp3 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • neuromuscular synaptic transmission
  • spermatid development
  • fertilization

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasm
  • manchette

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • benzodiazepine receptor binding

Gene-Specific Assays for Results You Can Trust

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