RIMBP3 Gene Summary [Human]

Predicted to enable benzodiazepine receptor binding activity. Predicted to be involved in fertilization and spermatid development. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Predicted to colocalize with manchette. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
RIMBP3
Official Name
RIMS binding protein 3 [Source:HGNC Symbol;Acc:HGNC:29344]
Ensembl ID
ENSG00000275793
Bio databases IDs NCBI: 85376 Ensembl: ENSG00000275793
Aliases RIMS binding protein 3
Synonyms Gm1759, Gm603, mKIAA1666, RGD1563657, RIM-BP3.1, RIMBP3A, RIM-BP3.A, RIMS binding protein 3
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RIMBP3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Domain of unknown function (DUF4515)
  • UDM1_RNF168_RNF169-like
  • FN3
  • Purple acid Phosphatase, N-terminal domain
  • protein binding
  • Fibronectin type 3 domain
  • Flagellar protein FliT
  • Src Homology 3 domain superfamily

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • oligozoospermia
regulated by
role in cell
  • formation
  • development
  • arrangement
  • abnormal morphology
  • fertilization
  • detachment

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • manchette
  • Nucleus

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human RIMBP3 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • neuromuscular synaptic transmission
  • spermatid development
  • fertilization

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasm
  • manchette

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • benzodiazepine receptor binding

Gene-Specific Assays for Results You Can Trust

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