Prkab2

Predicted to enable protein kinase binding activity. Predicted to contribute to AMP-activated protein kinase activity. Involved in positive regulation of cold-induced thermogenesis. Predicted to be located in apical plasma membrane. Predicted to be part of cAMP-dependent protein kinase complex and nucleotide-activated protein kinase complex. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; cardiovascular system; gallbladder; genitourinary system; and nervous system. Orthologous to human PRKAB2 (protein kinase AMP-activated non-catalytic subunit beta 2). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Prkab2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Prkab2 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Prkab2 gene, providing context for its role in the cell.