Vamp5 Gene Summary [Mouse]
Acts upstream of or within Golgi to plasma membrane protein transport and skeletal muscle tissue development. Located in several cellular components, including cytoplasmic vesicle; intercalated disc; and perinuclear region of cytoplasm. Orthologous to human VAMP5 (vesicle associated membrane protein 5). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Vamp5 |
| Official Name | vesicle-associated membrane protein 5 [Source:MGI Symbol;Acc:MGI:1858622] |
| Ensembl ID | ENSMUSG00000073002 |
| Bio databases IDs | |
| Aliases | vesicle-associated membrane protein 5 |
| Synonyms | AF119384, Camp, vesicle-associated membrane protein 5 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Vamp5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- SNARE motif
- Synaptobrevin
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- idiopathic scoliosis
- coronary artery disease
- myocardial infarction
- pervasive developmental disorder
role in cell
- fusion
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cytoplasmic vesicle membrane
- Cytoplasm
- cell surface
- perinuclear region
- intracellular membranes
- cellular membrane
- vesicles
- intercellular junctions
- trans Golgi network
- late endosomes
- perinuclear vesicles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Vamp5 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- muscle organ development
- skeletal muscle tissue development
- cell differentiation
- Golgi to plasma membrane protein transport
Cellular Component
Where in the cell the gene product is active
- cytoplasmic vesicle membrane
- perinuclear region of cytoplasm
- extracellular vesicular exosome
- late endosome
- intercalated disc
- Golgi apparatus
- organelle membrane
- plasma membrane
- cell surface
Molecular Function
What the gene product does at the molecular level
- protein binding