Pcdhb22 Gene Summary [Mouse]
Predicted to be involved in cell adhesion. Located in photoreceptor connecting cilium. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; liver; and retina. Orthologous to human PCDHB15 (protocadherin beta 15). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Pcdhb22 |
| Official Name | protocadherin beta 22 [Source:MGI Symbol;Acc:MGI:2136760] |
| Ensembl ID | ENSMUSG00000073591 |
| Bio databases IDs | |
| Aliases | protocadherin beta 22 |
| Synonyms | Pcdhb22, PCDH-BETA15, PcdhbV, protocadherin beta 15, protocadherin beta 22, protocadherin β 15, protocadherin β 22 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pcdhb22 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Cadherin-like
- Cadherin repeat-like domain
- Cadherin cytoplasmic C-terminal
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- cellular membrane
- Plasma Membrane
- connecting cilia
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Pcdhb22 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nervous system development
- cell adhesion
- homophilic cell adhesion
Cellular Component
Where in the cell the gene product is active
- photoreceptor connecting cilium
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- calcium ion binding