Cep192 Gene Summary [Mouse]
Predicted to enable phosphatase binding activity. Acts upstream of or within response to bacterium. Located in cytoplasm and pericentriolar material. Is expressed in cerebral cortex ventricular layer and meninges. Orthologous to human CEP192 (centrosomal protein 192). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cep192 |
| Official Name | centrosomal protein 192 [Source:MGI Symbol;Acc:MGI:1918049] |
| Ensembl ID | ENSMUSG00000024542 |
| Bio databases IDs | |
| Aliases | centrosomal protein 192 |
| Synonyms | 4631422C13Rik, centrosomal protein 192, D430014P18Rik, Da1-6, FLJ10352, PPP1R62, Seh1l |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cep192 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin
- protein binding
- phosphatase binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- breast carcinoma
- acute myeloid leukemia
- aortic valve calcification
role in cell
- replication
- assembly
- nucleation in
- nucleation
- spindle checkpoint
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- pericentrosomal region
- centrosome
- centriole
- cytosol
- pro-centriole
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cep192 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- response to bacterium
- centriole replication
- centrosome-templated microtubule nucleation
- protein localization to centrosome
- spindle assembly involved in mitosis
Cellular Component
Where in the cell the gene product is active
- pericentriolar material
- centrosome
- centriole
- cytoplasm
- cytosol
Molecular Function
What the gene product does at the molecular level
- phosphatase binding
- protein kinase binding
- protein binding