Kcng1 Gene Summary [Mouse]
Predicted to enable delayed rectifier potassium channel activity and potassium channel regulator activity. Predicted to be involved in action potential; potassium ion transmembrane transport; and regulation of potassium ion transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of voltage-gated potassium channel complex. Predicted to be active in membrane. Orthologous to human KCNG1 (potassium voltage-gated channel modifier subfamily G member 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Kcng1 |
| Official Name | potassium voltage-gated channel, subfamily G, member 1 [Source:MGI Symbol;Acc:MGI:3616086] |
| Ensembl ID | ENSMUSG00000074575 |
| Bio databases IDs | |
| Aliases | potassium voltage-gated channel, subfamily G, member 1 |
| Synonyms | AW536275, K13, KCNG, Kh2, KV6.1, potassium voltage-gated channel modifier subfamily G member 1, potassium voltage-gated channel, subfamily G, member 1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Kcng1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- delayed rectifier potassium channel
- Ion transport protein
- Broad-Complex, Tramtrack and Bric a brac
- BTB_POZ
- potassium channel regulator
- ion channel
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- uterine leiomyoma
- leiomyomatosis
- non-insulin-dependent diabetes mellitus
- bipolar disorder
- bipolar I disorder
- Cornelia de Lange syndrome
- major depression
regulates
- K+
role in cell
- replication in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Kcng1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- potassium ion transport
- potassium ion transmembrane transport
- protein homooligomerization
- regulation of action potential
Cellular Component
Where in the cell the gene product is active
- voltage-gated potassium channel complex
- membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- delayed rectifier potassium channel activity
- potassium channel activity