Smim26 Gene Summary [Mouse]
Predicted to enable protein kinase binding activity and transmembrane transporter binding activity. Located in mitochondrion. Orthologous to human SMIM26 (small integral membrane protein 26). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Smim26 |
| Official Name | small integral membrane protein 26 [Source:MGI Symbol;Acc:MGI:2685407] |
| Ensembl ID | ENSMUSG00000074754 |
| Bio databases IDs | |
| Aliases | small integral membrane protein 26 |
| Synonyms | Gm561, LINC00493, RGD1566320, small integral membrane protein 26 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Smim26 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein kinase binding
- ion channel binding
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- organismal death
- renal clear cell adenocarcinoma
- renal clear cell cancer
- metastasis
- renal cancer
regulated by
regulates
- AKT
- glutathione
- AGK
role in cell
- phosphorylation in
- migration
- cell viability
- invasion by
- colony formation
- mitochondrial respiration in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial outer membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Smim26 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- mitochondrial outer membrane
Molecular Function
What the gene product does at the molecular level
- protein kinase binding
- protein binding
- ion channel binding