Perm1 Gene Summary [Mouse]
Involved in regulation of DNA-templated transcription and response to muscle activity. Located in cytoplasm and nucleus. Is expressed in gastrocnemius muscle; heart; heart atrium; and heart ventricle. Orthologous to human PERM1 (PPARGC1 and ESRR induced regulator, muscle 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Perm1 |
| Official Name | PPARGC1 and ESRR induced regulator, muscle 1 [Source:MGI Symbol;Acc:MGI:1921433] |
| Ensembl ID | ENSMUSG00000078486 |
| Bio databases IDs | |
| Aliases | PPARGC1 and ESRR induced regulator, muscle 1 |
| Synonyms | 2310042D19Rik, C1orf170, PPARGC1 and ESRR induced regulator, muscle 1, RGD1304931 |
| Species | Mouse, Mus musculus |
| Orthologies |
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- heart failure
- congenital myasthenic syndrome type 8
role in cell
- expression in
- apoptosis
- activation in
- damage
- number
- production in
- downregulation in
- consumption in
- cellular respiration in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Perm1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- response to muscle activity
- regulation of transcription, DNA-dependent
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm