PERM1 Gene Summary [Human]
Involved in response to muscle activity. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | PERM1 |
| Official Name | PPARGC1 and ESRR induced regulator, muscle 1 [Source:HGNC Symbol;Acc:HGNC:28208] |
| Ensembl ID | ENSG00000187642 |
| Bio databases IDs | |
| Aliases | PPARGC1 and ESRR induced regulator, muscle 1, PGC-1- and ERR-induced regulator in muscle 1 |
| Synonyms | 2310042D19Rik, C1orf170, PPARGC1 and ESRR induced regulator, muscle 1, RGD1304931 |
| Species | Human, Homo sapiens |
| Orthologies |
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- heart failure
- congenital myasthenic syndrome type 8
role in cell
- expression in
- apoptosis
- activation in
- damage
- number
- production in
- downregulation in
- consumption in
- cellular respiration in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human PERM1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- response to muscle activity
- regulation of transcription, DNA-dependent
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm