Spaca6 Gene Summary [Mouse]
Predicted to enable protein-macromolecule adaptor activity. Involved in fusion of sperm to egg plasma membrane involved in single fertilization. Located in acrosomal vesicle. Orthologous to human SPACA6 (sperm acrosome associated 6). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Spaca6 |
| Official Name | sperm acrosome associated 6 [Source:MGI Symbol;Acc:MGI:1922452] |
| Ensembl ID | ENSMUSG00000080316 |
| Bio databases IDs | |
| Aliases | sperm acrosome associated 6 |
| Synonyms | 4930546H06Rik, 9530079D04RIK, B230206P06Rik, let-7e, LET7EH, LINC00085, LOC729781, mir-125a, mir-99b, NCRNA00085, SPACA6A, SPACA6P, sperm acrosome associated 6 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Spaca6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- immunoglobulin domain
- Immunoglobulin like
- protein binding activity, bridging
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- Plasma Membrane
- acrosome
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Spaca6 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- fusion of sperm to egg plasma membrane
Cellular Component
Where in the cell the gene product is active
- acrosomal membrane
Molecular Function
What the gene product does at the molecular level
- protein binding