Mfsd14a Gene Summary [Mouse]
Predicted to enable transmembrane transporter activity. Acts upstream of or within acrosome assembly; sperm mitochondrion organization; and spermatid nucleus differentiation. Predicted to be located in membrane. Is expressed in several structures, including brain; genitourinary system; liver; lung; and spleen. Orthologous to human MFSD14A (major facilitator superfamily domain containing 14A). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mfsd14a |
| Official Name | major facilitator superfamily domain containing 14A [Source:MGI Symbol;Acc:MGI:1201609] |
| Ensembl ID | ENSMUSG00000089911 |
| Bio databases IDs | |
| Aliases | major facilitator superfamily domain containing 14A |
| Synonyms | HAIT1, HIAT1, major facilitator superfamily domain containing 14A |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mfsd14a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Nucleoside H+ symporter
- MFS_1 like family
- Major Facilitator Superfamily
- drug resistance transporter, Bcr/CflA subfamily
- transporter
- MFS/sugar transport protein
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mfsd14a gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- acrosome assembly
- transmembrane transport
- sperm mitochondrion organization
- spermatid nucleus differentiation
Cellular Component
Where in the cell the gene product is active
- membrane
Molecular Function
What the gene product does at the molecular level
- transmembrane transporter activity