Gimap1 Gene Summary [Mouse]

This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. Sequence analysis identified two alternatively spliced variants that encode the same protein. [provided by RefSeq, Jul 2008]

Details

Type
Protein Coding
Official Symbol
Gimap1
Official Name
GTPase, IMAP family member 1 [Source:MGI Symbol;Acc:MGI:109368]
Ensembl ID
ENSMUSG00000090019
Bio databases IDs NCBI: 16205 Ensembl: ENSMUSG00000090019
Aliases GTPase, IMAP family member 1
Synonyms GTPase, IMAP family member 1, HIMAP1, IAN2, IAP38, imap, IMAP1, IMAP38
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gimap1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • GTP binding
  • 50S ribosome-binding GTPase
  • protein binding
  • P-loop containing Nucleoside Triphosphate Hydrolases
  • AIG1 family

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Behcet disease
regulated by
role in cell
  • proliferation
  • differentiation
  • apoptosis
  • survival
  • number
  • deficiency
  • depolarization in
  • depolarization

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Nucleus
  • Endoplasmic Reticulum
  • endoplasmic reticulum membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Gimap1 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • endoplasmic reticulum membrane
  • Golgi membrane
  • endoplasmic reticulum

Molecular Function

What the gene product does at the molecular level
  • GTP binding
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.