GTPase, IMAP family member 1 [Source:NCBI gene;Acc:312312]
GTPase, IMAP family member 1 [Source:NCBI gene;Acc:312312] Gene Summary [Rat]
Predicted to enable GTP binding activity. Predicted to act upstream of or within B cell differentiation; CD4-positive, alpha-beta T cell differentiation; and CD8-positive, alpha-beta T cell differentiation. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum. Orthologous to human GIMAP1 (GTPase, IMAP family member 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | GTPase, IMAP family member 1 [Source:NCBI gene;Acc:312312] |
| Official Name | GTPase, IMAP family member 1 [Source:NCBI gene;Acc:312312] |
| Ensembl ID | ENSRNOG00000042229 |
| Bio databases IDs | |
| Aliases | GTPase, IMAP family member 1 |
| Synonyms | GTPase, IMAP family member 1, HIMAP1, IAN2, IAP38, imap, IMAP1, IMAP38 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Gtpase, Imap Family Member 1 [Source:Ncbi Gene;Acc:312312] often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- GTP binding
- 50S ribosome-binding GTPase
- protein binding
- P-loop containing Nucleoside Triphosphate Hydrolases
- AIG1 family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- Behcet disease
role in cell
- proliferation
- differentiation
- apoptosis
- survival
- number
- deficiency
- depolarization in
- depolarization
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- Endoplasmic Reticulum
- endoplasmic reticulum membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Gtpase, Imap Family Member 1 [Source:Ncbi Gene;Acc:312312] gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- Golgi membrane
- endoplasmic reticulum
Molecular Function
What the gene product does at the molecular level
- GTP binding
- protein binding