Pcdhga4 Gene Summary [Mouse]
Predicted to enable calcium ion binding activity. Predicted to be involved in cell adhesion. Located in membrane. Is expressed in brain; cerebellum Purkinje cell layer; cerebral cortex; and hippocampus CA3. Orthologous to human PCDHGA4 (protocadherin gamma subfamily A, 4). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Pcdhga4 |
| Official Name | protocadherin gamma subfamily A, 4 [Source:MGI Symbol;Acc:MGI:1935216] |
| Ensembl ID | ENSMUSG00000103677 |
| Bio databases IDs | |
| Aliases | protocadherin gamma subfamily A, 4 |
| Synonyms | Pcdhga3, PCDH-GAMMA-A4, PCDH-γ-A4, protocadherin gamma subfamily A, 4, protocadherin γ subfamily A, 4 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pcdhga4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Cadherin-like
- Cadherin repeat-like domain
- protein binding
- Cadherin cytoplasmic C-terminal
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Pcdhga4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nervous system development
- cell adhesion
- homophilic cell adhesion
Cellular Component
Where in the cell the gene product is active
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- calcium ion binding