Kifbp Gene Summary [Rat]
Predicted to enable kinesin binding activity and protein sequestering activity. Predicted to be involved in microtubule cytoskeleton organization; mitochondrion transport along microtubule; and plasma membrane bounded cell projection organization. Predicted to act upstream of or within in utero embryonic development. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in Goldberg-Shprintzen syndrome. Orthologous to human KIFBP (kinesin family binding protein). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Kifbp |
| Official Name | kinesin family binding protein [Source:RGD Symbol;Acc:1593126] |
| Ensembl ID | ENSRNOG00000000395 |
| Bio databases IDs | |
| Aliases | kinesin family binding protein |
| Synonyms | 0710007C18Rik, 2510003E04Rik, DKFZp586B0923, KBP, KIAA1279, KIF1BP, kinesin family binding protein, mKIAA1279, TTC20 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Kifbp often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- enzyme
- KIF-1 binding protein C terminal
- protein binding
- kinesin binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Kifbp gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- in utero embryonic development
- mitochondrion transport along microtubule
- central nervous system projection neuron axonogenesis
- microtubule cytoskeleton organization
- microtubule-based transport
Cellular Component
Where in the cell the gene product is active
- cytoskeleton
- mitochondrion
Molecular Function
What the gene product does at the molecular level
- protein binding
- kinesin binding