Rilpl1 Gene Summary [Rat]
Predicted to enable dynein light intermediate chain binding activity and small GTPase binding activity. Involved in nitric oxide mediated signal transduction. Located in cytosol. Human ortholog(s) of this gene implicated in oculopharyngodistal myopathy 4. Orthologous to human RILPL1 (Rab interacting lysosomal protein like 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rilpl1 |
| Official Name | Rab interacting lysosomal protein-like 1 [Source:RGD Symbol;Acc:1307973] |
| Ensembl ID | ENSRNOG00000001055 |
| Bio databases IDs | |
| Aliases | Rab interacting lysosomal protein-like 1 |
| Synonyms | 2900002H16Rik, 6330559I19Rik, GOSPEL, OPDM4, Rab interacting lysosomal protein-like 1, RGD1307973, RLP1 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Rilpl1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Rab interacting lysosomal protein
- protein binding
- JNK_SAPK-associated protein-1
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- mother centriole
- cilia
- Plasma Membrane
- basal bodies
- centrosome
- cytosol
- primary cilia
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Rilpl1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nitric oxide mediated signal transduction
- cilium morphogenesis
- epithelial cell morphogenesis
Cellular Component
Where in the cell the gene product is active
- centrosome
- centriole
- cilium basal body
- cytoplasm
- cilium
- cytosol
- plasma membrane
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- dynein light intermediate chain binding
- small GTPase binding
- protein dimerization activity