Asmt Gene Summary [Rat]
Enables acetylserotonin O-methyltransferase activity. Involved in melatonin biosynthetic process. Orthologous to human ASMT (acetylserotonin O-methyltransferase). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Asmt |
| Official Name | acetylserotonin O-methyltransferase [Source:RGD Symbol;Acc:708472] |
| Ensembl ID | ENSRNOG00000001324 |
| Bio databases IDs | |
| Aliases | acetylserotonin O-methyltransferase |
| Synonyms | acetylserotonin O-methyltransferase, ASMTY, HIOMT, HIOMTY, LOC246281 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Asmt often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- O-methyltransferase
- dimerization domain
- acetylserotonin O-methyltransferase
- S-methyltransferase
- protein homodimerization
- enzyme
- AdoMet_MTases
- methyltransferase domain
- S-adenosylmethionine-dependent methyltransferase
- identical protein binding
Pathways
Biological processes and signaling networks where the Asmt gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Asmt gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- lipid metabolic process
- melatonin biosynthetic process
- indolalkylamine biosynthetic process
- translation
- methylation
Cellular Component
Where in the cell the gene product is active
- cytosol
Molecular Function
What the gene product does at the molecular level
- S-methyltransferase activity
- O-methyltransferase activity
- identical protein binding
- protein homodimerization activity
- acetylserotonin O-methyltransferase activity