Col26a1 Gene Summary [Rat]

Predicted to act upstream of or within positive regulation of cell-substrate adhesion. Predicted to be located in Golgi apparatus; endoplasmic reticulum; and extracellular matrix. Orthologous to human COL26A1 (collagen type XXVI alpha 1 chain). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Col26a1
Official Name
collagen type XXVI alpha 1 chain [Source:RGD Symbol;Acc:1591401]
Ensembl ID
ENSRNOG00000001422
Bio databases IDs NCBI: 685612 Ensembl: ENSRNOG00000001422
Aliases collagen type XXVI alpha 1 chain
Synonyms 9430032K24Rik, Col26a, Collagen Type26, collagen, type XXVI, alpha 1, collagen type XXVI alpha 1 chain, collagen, type XXVI, α 1, collagen type XXVI α 1 chain, EMI6, EMID2, EMU2, LOC686428, SH2B
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Col26a1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • EMI domain
  • protein binding

Pathways

Biological processes and signaling networks where the Col26a1 gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • neoplasia
  • acute myeloid leukemia
  • survival
  • inguinal hernia
  • cleft lip
regulated by
  • dexamethasone
  • Borrelia burgdorferi strain HB19
  • LDB1
  • D-alpha-hydroxyglutarate
  • ZNF106
  • BB0603
regulates
role in cell
  • maturation in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • Plasma Membrane
  • Golgi Apparatus
  • Endoplasmic Reticulum
  • endoplasmic reticulum lumen
  • extracellular matrix

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Col26a1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • positive regulation of cell-substrate adhesion

Cellular Component

Where in the cell the gene product is active
  • endoplasmic reticulum lumen
  • Golgi apparatus
  • extracellular region
  • plasma membrane

Gene-Specific Assays for Results You Can Trust

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