Prkrip1 Gene Summary [Rat]

Predicted to enable double-stranded RNA binding activity; protein kinase binding activity; and protein kinase inhibitor activity. Involved in renal system process. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
Prkrip1
Official Name
PRKR interacting protein 1 [Source:RGD Symbol;Acc:1595708]
Ensembl ID
ENSRNOG00000001426
Bio databases IDs NCBI: 498171 Ensembl: ENSRNOG00000001426
Aliases PRKR interacting protein 1
Synonyms 8430424D23Rik, C114, KRBOX3, PRKR interacting protein 1, Prkr interacting protein 1 (IL11 inducible)
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Prkrip1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein kinase binding
  • protein kinase inhibitor activity
  • double-stranded RNA binding
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • non-insulin-dependent diabetes mellitus
  • insomnia
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoplasm
  • nucleoli

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Prkrip1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • RNA splicing
  • mRNA processing
  • negative regulation of protein kinase activity
  • renal system process
  • negative regulation of phosphorylation

Cellular Component

Where in the cell the gene product is active
  • extracellular vesicular exosome
  • spliceosomal complex
  • nucleolus
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein kinase binding
  • protein binding
  • double-stranded RNA binding
  • protein kinase inhibitor activity

Gene-Specific Assays for Results You Can Trust

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