Snrpa Gene Summary [Rat]
Enables U1 snRNP binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Part of U1 snRNP. Human ortholog(s) of this gene implicated in connective tissue disease. Orthologous to human SNRPA (small nuclear ribonucleoprotein polypeptide A). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Snrpa |
| Official Name | small nuclear ribonucleoprotein polypeptide A [Source:RGD Symbol;Acc:1307416] |
| Ensembl ID | ENSRNOG00000001501 |
| Bio databases IDs | |
| Aliases | small nuclear ribonucleoprotein polypeptide A |
| Synonyms | C430021M15RIK, Mud1, Rnu1a-1, small nuclear ribonucleoprotein polypeptide A, U1-A, U1 SNRNP-SPECIFIC protein A |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Snrpa often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- U1 snRNA binding
- RNA recognition motif (RRM) superfamily
- RNA recognition motif
- nuclear localization sequence
- ribonucleoprotein binding
- protein binding
- identical protein binding
- DNA binding
- RNA binding
Pathways
Biological processes and signaling networks where the Snrpa gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- stomach disorder
- Alzheimer disease
- spliceosomepathy
- infection by HIV-1
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nuclear fraction
- spliceosomes
- nucleoplasm
- interchromatin granule clusters
- cytosolic fraction
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Snrpa gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nuclear mRNA splicing, via spliceosome
Cellular Component
Where in the cell the gene product is active
- nucleus
- U4/U6 x U5 tri-snRNP complex
- spliceosomal complex
- U1 snRNP
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- DNA binding
- identical protein binding
- protein binding
- RNA binding
- U1 snRNA binding