Tmprss15 Gene Summary [Rat]
Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be active in membrane. Human ortholog(s) of this gene implicated in enterokinase deficiency. Orthologous to human TMPRSS15 (transmembrane serine protease 15). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tmprss15 |
| Official Name | transmembrane serine protease 15 [Source:RGD Symbol;Acc:1311046] |
| Ensembl ID | ENSRNOG00000001916 |
| Bio databases IDs | |
| Aliases | transmembrane serine protease 15 |
| Synonyms | enterokinase, ENTEROPEPTIDASE, ENTK, proenterokinase, PRSS7, transmembrane protease, serine 15, transmembrane serine protease 15 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Tmprss15 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Scavenger receptor cysteine-rich domain
- Trypsin-like serine protease
- Tryp_SPc
- enteropeptidase
- peptidase
- SEA domain
- protein binding
- Scavenger receptor Cys-rich
- Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)
- trypsin
- CUB
- LDLa
- MAM domain, meprin/A5/mu
Pathways
Biological processes and signaling networks where the Tmprss15 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- cellular membrane
- brush border
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Tmprss15 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- proteolysis
Cellular Component
Where in the cell the gene product is active
- brush border
- membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- serine-type endopeptidase activity