Mrpl1 Gene Summary [Rat]

Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in mitochondrion and ribosome. Predicted to be part of large ribosomal subunit. Orthologous to human MRPL1 (mitochondrial ribosomal protein L1). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Mrpl1
Official Name
mitochondrial ribosomal protein L1 [Source:RGD Symbol;Acc:1306850]
Ensembl ID
ENSRNOG00000002070
Bio databases IDs NCBI: 289491 Ensembl: ENSRNOG00000002070
Aliases mitochondrial ribosomal protein L1
Synonyms 2410002L03Rik, 5830418D04Rik, AI462572, BM-022, L1MT, LOC100359687, mitochondrial ribosomal protein L1, uL1m
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Mrpl1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Ribosomal_L1
  • structural constituent of ribosome
  • Ribosomal protein L1p/L10e family
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • headache
  • nonalcoholic fatty liver disease
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • ribosome
  • Nucleus
  • mitochondrial inner membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Mrpl1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • mitochondrial translation

Cellular Component

Where in the cell the gene product is active
  • mitochondrial large ribosomal subunit
  • mitochondrial inner membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • RNA binding
  • structural constituent of ribosome

Gene-Specific Assays for Results You Can Trust

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