Gtf2b

Predicted to enable several functions, including RNA polymerase II core promoter sequence-specific DNA binding activity; RNA polymerase II general transcription initiation factor activity; and TBP-class protein binding activity. Predicted to be involved in several processes, including RNA polymerase II core complex assembly; meiotic sister chromatid cohesion; and transcription initiation at RNA polymerase II promoter. Predicted to be located in chromosome and nuclear body. Predicted to be part of transcription factor TFIID complex and transcription preinitiation complex. Predicted to be active in cell division site; germinal vesicle; and kinetochore. Orthologous to human GTF2B (general transcription factor IIB). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Gtf2b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Gtf2b gene in rat plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the rat Gtf2b gene, providing context for its role in the cell.