Myo1d Gene Summary [Rat]
Enables several functions, including actin filament binding activity; calcium-dependent protein binding activity; and calmodulin binding activity. Involved in forebrain development. Located in several cellular components, including apical dendrite; axolemma; and basolateral plasma membrane. Part of myosin complex. Orthologous to human MYO1D (myosin ID). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Myo1d |
| Official Name | myosin ID [Source:RGD Symbol;Acc:621321] |
| Ensembl ID | ENSRNOG00000003276 |
| Bio databases IDs | |
| Aliases | myosin ID |
| Synonyms | 9930104H07RIK, AW544947, D11Ertd9e, LOC102724697, Myo1c, myosin-1d, myosin ID, Myr2, Myr4, PPP1R108 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Myo1d often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- actin filament binding
- calcium-dependent protein binding
- Myosin and Kinesin motor domain
- calmodulin binding
- microfilament motor protein
- protein domain specific binding
- enzyme
- protein binding
- Unconventional myosin tail, actin- and lipid-binding
- Myosin
- Myosin head (motor domain)
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- chronic obstructive pulmonary disease
- Dupuytren contracture
- inguinal hernia
- pancreatic carcinoma
- pancreatic epithelial cancer
- refractive error
- age-related hearing loss
- hypertension
- myopia
- anorexia nervosa
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- myelin enriched fraction
- endosomes
- microvilli tips
- basolateral membrane
- axonal membrane
- neurites
- myelin sheath
- cytoplasmic vesicles
- membrane rafts
- brush border
- perikaryon
- axons
- apical processes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Myo1d gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cellular localization
- protein transport
- actin filament organization
- actin filament-based movement
- endocytosis
Cellular Component
Where in the cell the gene product is active
- myosin complex
- myelin sheath
- smooth endoplasmic reticulum
- neuronal cell body
- perikaryon
- neuron projection
- plasma membrane
- early endosome
- extracellular vesicular exosome
- endosome
- brush border
- cytoplasm
- microvillus
- cell cortex
- actin cytoskeleton
- cytoplasmic vesicle
- axolemma
- basolateral plasma membrane
- axon
Molecular Function
What the gene product does at the molecular level
- actin filament binding
- ATP binding
- protein domain specific binding
- calmodulin binding
- calcium-dependent protein binding
- microfilament motor activity