Cpd Gene Summary [Rat]

Enables protein phosphatase 2A binding activity. Involved in cellular response to interleukin-2. Located in nucleus; perinuclear region of cytoplasm; and trans-Golgi network. Orthologous to human CPD (carboxypeptidase D). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Cpd
Official Name
carboxypeptidase D [Source:RGD Symbol;Acc:2393]
Ensembl ID
ENSRNOG00000003873
Bio databases IDs NCBI: 25306 Ensembl: ENSRNOG00000003873
Aliases carboxypeptidase D
Synonyms AW322530, carboxypeptidase D, D830034L15RIK, DKFZP564P046, GP180
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cpd often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Zn_pept domain
  • protein phosphatase binding
  • peptidase
  • metallocarboxypeptidase
  • M14 family of metallocarboxypeptidases and related proteins
  • Carboxypeptidase regulatory-like domain
  • Zinc carboxypeptidase
  • binding protein
  • cytoplasmic domain
  • zinc ion binding
  • serine-type carboxypeptidase
  • Peptidase_M14NE-CP-C_like
  • CarboxypepD_reg-like domain

Pathways

Biological processes and signaling networks where the Cpd gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • lung adenocarcinoma
  • lung adenocarcinoma formation
  • organismal death
  • preeclampsia
regulated by
  • dexamethasone
  • filgrastim
  • D-glucose
  • bleomycin
  • Tgfb
  • AKT
  • CREB1
  • IFNG
  • Immunoglobulin
  • MYC
regulates
  • nitric oxide
  • CPD
role in cell
  • quantity

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • endoplasmic reticulum mitochondria contact site
  • perinuclear region
  • cellular membrane
  • Nucleus
  • Plasma Membrane
  • vesicles
  • trans Golgi network
  • secretory vesicles

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Cpd gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • peptide metabolic process
  • protein processing

Cellular Component

Where in the cell the gene product is active
  • extracellular space
  • extracellular vesicular exosome
  • membrane
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • zinc ion binding
  • metallocarboxypeptidase activity
  • serine-type carboxypeptidase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.