Mfsd2a

Predicted to enable lysophosphatidylcholine flippase activity; lysophospholipid:sodium symporter activity; and oleate transmembrane transporter activity. Predicted to be involved in several processes, including central nervous system development; lipid transport across blood-brain barrier; and lysophospholipid translocation. Predicted to act upstream of or within several processes, including photoreceptor cell development; regulation of lipid metabolic process; and retina development in camera-type eye. Predicted to be located in cytoplasmic ribonucleoprotein granule and cytosol. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 15. Orthologous to human MFSD2A (MFSD2 lysolipid transporter A, lysophospholipid). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Mfsd2a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Mfsd2a gene in rat plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the rat Mfsd2a gene, providing context for its role in the cell.