Fmc1 Gene Summary [Rat]

Predicted to be involved in mitochondrial proton-transporting ATP synthase complex assembly. Predicted to act upstream of or within several processes, including dopaminergic neuron differentiation; motor behavior; and regulation of type B pancreatic cell proliferation. Predicted to be active in mitochondrion. Orthologous to several human genes including FMC1 (formation of mitochondrial complex V assembly factor 1 homolog). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Fmc1
Official Name
formation of mitochondrial complex V assembly factor 1 [Source:RGD Symbol;Acc:1559476]
Ensembl ID
ENSRNOG00000005618
Bio databases IDs NCBI: 500087 Ensembl: ENSRNOG00000005618
Aliases formation of mitochondrial complex V assembly factor 1
Synonyms 1110001J03Rik, C7orf55, formation of mitochondrial complex V assembly factor 1, formation of mitochondrial complex V assembly factor 1 homolog, HSPC268
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Fmc1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • LYR (leucine-tyrosine-arginine) motif found in Complex1_LYR-like superfamily

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
regulates
  • lipid
role in cell
  • differentiation
  • organization
  • morphology

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Mitochondria

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Fmc1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • mitochondrial proton-transporting ATP synthase complex assembly
  • negative regulation of lipid catabolic process

Cellular Component

Where in the cell the gene product is active
  • mitochondrion

Molecular Function

What the gene product does at the molecular level
  • protein binding