Oxsm Gene Summary [Rat]
This gene encodes a beta-ketoacyl synthetase. The encoded enzyme is required for elongation of fatty acid chains in the mitochondria. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2009]
Details
| Type | Protein Coding |
| Official Symbol | Oxsm |
| Official Name | 3-oxoacyl-ACP synthase, mitochondrial [Source:RGD Symbol;Acc:1311092] |
| Ensembl ID | ENSRNOG00000005993 |
| Bio databases IDs | |
| Aliases | 3-oxoacyl-ACP synthase, mitochondrial |
| Synonyms | 3-oxoacyl-ACP synthase, mitochondrial, 4933425A18RIK, C80494, CEM1, FASN2D, FLJ20604, KASI, KS, LOC498451, RGD1311092 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Oxsm often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- kinase
- cond_enzymes
- 3-oxoacyl-[acyl-carrier-protein] synthase
- beta-ketoacyl-acyl-carrier-protein synthase II
- Beta-ketoacyl synthase, C-terminal domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- psoriasis
- diabetic nephropathy
regulates
- reactive oxygen species
- acyl-coenzyme A
- medium chain fatty acid
- short chain fatty acid
- PRKN
- fatty acid
role in cell
- proliferation
- cell viability
- function
- function in
- cohesion in
- cohesion
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- cytosol
- mitochondrial matrix
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Oxsm gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- acyl-CoA metabolic process
- medium-chain fatty acid biosynthetic process
- short-chain fatty acid biosynthetic process
- fatty acid biosynthetic process
Cellular Component
Where in the cell the gene product is active
- mitochondrial matrix
- mitochondrion
- cytosol
Molecular Function
What the gene product does at the molecular level
- 3-oxoacyl-[acyl-carrier-protein] synthase activity