Cfap69

Predicted to be involved in several processes, including positive regulation of fertilization; positive regulation of flagellated sperm motility; and response to odorant. Predicted to act upstream of or within sperm axoneme assembly. Predicted to be located in cytoplasm. Predicted to be active in non-motile cilium and sperm midpiece. Human ortholog(s) of this gene implicated in spermatogenic failure 24. Orthologous to human CFAP69 (cilia and flagella associated protein 69). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cfap69 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the rat Cfap69 gene, providing context for its role in the cell.