CFAP69 Gene Summary [Human]
Acts upstream of or within sperm axoneme assembly. Located in cytoplasm and sperm midpiece. Implicated in spermatogenic failure 24. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | CFAP69 |
| Official Name | cilia and flagella associated protein 69 [Source:HGNC Symbol;Acc:HGNC:26107] |
| Ensembl ID | ENSG00000105792 |
| Bio databases IDs | |
| Aliases | cilia and flagella associated protein 69, hypothetical protein FLJ21062, flagellar protein 69 homolog (Chlamydomonas) |
| Synonyms | 4921525K03, A330021E22Rik, C7orf63, cilia and flagella associated protein 69, FAP69, FLJ21062, LOC679610, LOC682900, MGC72627, SPGF24 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CFAP69 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- non-motile cilium
- cilia
- sperm midpiece
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CFAP69 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- sperm motility
- sensory perception of smell
- sperm axoneme assembly
- olfactory behavior
Cellular Component
Where in the cell the gene product is active
- sperm midpiece
- cytoplasm