Fam83a Gene Summary [Rat]
Predicted to enable identical protein binding activity; phosphatidylinositol 3-kinase regulatory subunit binding activity; and protein kinase binding activity. Predicted to be involved in cell population proliferation and epidermal growth factor receptor signaling pathway. Orthologous to human FAM83A (family with sequence similarity 83 member A). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Fam83a |
| Official Name | family with sequence similarity 83, member A [Source:RGD Symbol;Acc:1565606] |
| Ensembl ID | ENSRNOG00000006251 |
| Bio databases IDs | |
| Aliases | family with sequence similarity 83, member A |
| Synonyms | AC113292.4, BJ-TSA-9, family with sequence similarity 83 member A, family with sequence similarity 83, member A, RGD1565606 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Fam83a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- phosphoinositide 3-kinase binding
- protein kinase binding
- FAM83 A-H
- protein binding
- Catalytic domain of phospholipase D superfamily proteins
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- lung adenocarcinoma formation
- lung adenocarcinoma
regulated by
role in cell
- production in
- proliferation
- expression in
- differentiation
- molecular cleavage in
- formation
- formation in
- permeability
- area
- copy number
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Fam83a gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell proliferation
- epidermal growth factor receptor signaling pathway
Cellular Component
Where in the cell the gene product is active
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- protein kinase binding
- identical protein binding
- protein binding