Mdm1 Gene Summary [Rat]
Predicted to enable microtubule binding activity. Predicted to be involved in negative regulation of centriole replication and retina development in camera-type eye. Predicted to be located in several cellular components, including cytosol; microtubule organizing center; and non-motile cilium. Orthologous to human MDM1 (Mdm1 nuclear protein). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mdm1 |
| Official Name | Mdm1 nuclear protein [Source:RGD Symbol;Acc:1561092] |
| Ensembl ID | ENSRNOG00000007286 |
| Bio databases IDs | |
| Aliases | Mdm1 nuclear protein |
| Synonyms | Arrd2, MDM1 nuclear protein |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Mdm1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- microtubule binding
- protein binding
- Nuclear protein MDM1
- zDHHC ankyrin repeat binding domain
- HR1
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- non-motile cilium
- Nucleus
- centrosome
- centriole
- cytosol
- cytoplasmic microtubule
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Mdm1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- retina development in camera-type eye
- negative regulation of centriole replication
Cellular Component
Where in the cell the gene product is active
- nucleus
- centrosome
- centriole
- centriolar satellite
- cytosol
- microtubule
Molecular Function
What the gene product does at the molecular level
- protein binding
- microtubule binding