Golga5 Gene Summary [Rat]

Enables protein-macromolecule adaptor activity and small GTPase binding activity. Involved in Golgi organization and retrograde transport, vesicle recycling within Golgi. Located in COPI-coated vesicle membrane and Golgi apparatus. Orthologous to human GOLGA5 (golgin A5). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Golga5
Official Name
golgin A5 [Source:RGD Symbol;Acc:1308163]
Ensembl ID
ENSRNOG00000007699
Bio databases IDs NCBI: 299258 Ensembl: ENSRNOG00000007699
Aliases golgin A5
Synonyms golgin A5, GOLIM5, Ret-II, RFG5
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Golga5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Crescentin protein
  • Autophagy protein 16 (ATG16)
  • protein binding activity, bridging
  • enzyme binding
  • coiled-coil domain
  • protein binding
  • Calcium binding and coiled-coil domain (CALCOCO1) like
  • Golgin subfamily A member 5
  • kinase
  • Domain of unknown function (DUF4686)
  • transmembrane domain
  • Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
  • protein homodimerization
  • Intermediate filament protein
  • Outer membrane protein (OmpH-like)
  • Septation ring formation regulator, EzrA

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
regulates
  • Vsvg
role in cell
  • transformation
  • organization
  • volume
  • fragmentation
  • transport
  • conversion

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Golgi-enriched fraction
  • cellular membrane
  • Golgi Apparatus
  • Golgi membrane
  • cis Golgi networks
  • transport vesicles
  • Golgi cisternae

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Golga5 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • Golgi organization
  • retrograde transport, vesicle recycling within Golgi
  • Golgi vesicle transport

Cellular Component

Where in the cell the gene product is active
  • cis-Golgi network
  • membrane
  • Golgi apparatus
  • Golgi membrane
  • transport vesicle
  • Golgi cisterna

Molecular Function

What the gene product does at the molecular level
  • protein homodimerization activity
  • small GTPase binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.