Ssbp3 Gene Summary [Rat]
Predicted to enable transcription coactivator activity. Predicted to be involved in several processes, including head morphogenesis; nervous system development; and positive regulation of anterior head development. Predicted to act upstream of or within hematopoietic progenitor cell differentiation. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Orthologous to human SSBP3 (single stranded DNA binding protein 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ssbp3 |
| Official Name | single stranded DNA binding protein 3 [Source:RGD Symbol;Acc:621502] |
| Ensembl ID | ENSRNOG00000007920 |
| Bio databases IDs | |
| Aliases | single stranded DNA binding protein 3 |
| Synonyms | 2610021L12Rik, 2610200M23Rik, 5730488C10Rik, CSDP, LAST, LOC102549605, single-stranded DNA binding protein 3, SSDP, SSDP1, Ssdp3 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ssbp3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transcription regulator
- transcription co-activator
- single-stranded DNA binding
- protein binding
- Single-stranded DNA binding protein, SSDP
- LisH
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- epithelial cancer
- prostate cancer
- prostatic carcinoma
- Fuchs endothelial dystrophy
- group 3 medulloblastoma
- brain cancer
- metabolic syndrome X
- hyperopia
- abdominal aortic aneurysm
regulates
- DNA promoter
- DNA endogenous promoter
- RNA polymerase II
- histone H3
- protein-protein complex
- histone H2B
role in cell
- proliferation
- differentiation
- growth
- mono-ubiquitination in
- trimethylation in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nuclear fraction
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Ssbp3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- macromolecular complex assembly
- positive regulation of cell proliferation
- prechordal plate formation
- positive regulation of anterior head development
- midbrain-hindbrain boundary initiation
- positive regulation of transcription from RNA polymerase II promoter
- mesendoderm development
- head morphogenesis
- hemopoietic progenitor cell differentiation
Cellular Component
Where in the cell the gene product is active
- nucleus
- transcription factor complex
Molecular Function
What the gene product does at the molecular level
- protein binding
- transcription coactivator activity
- single-stranded DNA binding