Fscn3 Gene Summary [Rat]
Predicted to enable actin filament binding activity. Predicted to be involved in actin filament bundle assembly; cell migration; and establishment or maintenance of cell polarity. Predicted to be active in several cellular components, including lamellipodium; microvillus; and ruffle. Orthologous to human FSCN3 (fascin actin-bundling protein 3). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Fscn3 |
| Official Name | fascin actin-bundling protein 3 [Source:RGD Symbol;Acc:1303047] |
| Ensembl ID | ENSRNOG00000007942 |
| Bio databases IDs | |
| Aliases | fascin actin-bundling protein 3 |
| Synonyms | fascin actin-bundling protein 3 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Fscn3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- actin filament binding
- fascin-like domain, beta-trefoil fold, found in the fascin-like family
- actin binding
- Fascin domain
Pathways
Biological processes and signaling networks where the Fscn3 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytoskeleton
- actin cytoskeleton
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Fscn3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- establishment or maintenance of cell polarity
- cell migration
- actin filament bundle assembly
Cellular Component
Where in the cell the gene product is active
- growth cone
- cytoskeleton
- cytoplasm
- microvillus
- ruffle
- actin cytoskeleton
- filopodium
- cell projection membrane
- lamellipodium
Molecular Function
What the gene product does at the molecular level
- actin filament binding
- protein binding, bridging