Hspb11 Gene Summary [Rat]
Predicted to be involved in kidney development; smoothened signaling pathway; and spermatogenesis. Predicted to act upstream of or within several processes, including left/right axis specification; lung development; and skeletal system development. Predicted to be part of intraciliary transport particle B. Predicted to be active in centrosome and cilium. Orthologous to human IFT25 (intraflagellar transport 25). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Hspb11 |
| Official Name | heat shock protein family B (small), member 11 [Source:RGD Symbol;Acc:1596413] |
| Ensembl ID | ENSRNOG00000010241 |
| Bio databases IDs | |
| Aliases | heat shock protein family B (small), member 11 |
| Synonyms | 2900042B11Rik, C1orf41, CFAP232, FAP232, HSP16.2, HSPB11, HSPCO34, intraflagellar transport 25, LOC683481, MGC897N, PP25 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Hspb11 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- F5/8 type C domain
- protein binding
Pathways
Biological processes and signaling networks where the Hspb11 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- ciliary tip
- cilia
- centrosome
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Hspb11 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- heart development
- skeletal system development
- cilium morphogenesis
- kidney development
- spermatogenesis
- protein transport
- cell differentiation
- smoothened signaling pathway
- intraflagellar anterograde transport
- left/right axis specification
- lung development
Cellular Component
Where in the cell the gene product is active
- centrosome
- cilium
- intraflagellar transport particle B
Molecular Function
What the gene product does at the molecular level
- protein binding
- metal ion binding