Slc25a4

Enables enzyme binding activity. Involved in several processes, including negative regulation of cardiac muscle cell apoptotic process; negative regulation of mitochondrial membrane permeability involved in apoptotic process; and positive regulation of cell growth involved in cardiac muscle cell development. Located in membrane raft; mitochondrial inner membrane; and mitochondrial outer membrane. Biomarker of alcoholic cardiomyopathy. Human ortholog(s) of this gene implicated in intrinsic cardiomyopathy (multiple); mitochondrial DNA depletion syndrome (multiple); and mitochondrial myopathy (multiple). Orthologous to human SLC25A4 (solute carrier family 25 member 4). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Slc25a4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Slc25a4 gene in rat plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the rat Slc25a4 gene, providing context for its role in the cell.