Cmbl Gene Summary [Rat]

Predicted to enable hydrolase activity. Predicted to be located in cytosol and membrane. Orthologous to human CMBL (carboxymethylenebutenolidase homolog). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Cmbl
Official Name
carboxymethylenebutenolidase homolog [Source:RGD Symbol;Acc:1306952]
Ensembl ID
ENSRNOG00000011260
Bio databases IDs NCBI: 310201 Ensembl: ENSRNOG00000011260
Aliases carboxymethylenebutenolidase homolog
Synonyms 2310016A09Rik, carboxymethylenebutenolidase homolog, JS-1, LOC134147, RGD1306952
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cmbl often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Dienelactone hydrolase family
  • alpha/beta hydrolases
  • enzyme
  • hydrolase

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • epithelial cancer
  • hepatocellular carcinoma
  • liver cancer
regulated by
regulates
  • olmesartan
  • olmesartan medoxomil
  • xenobiotic

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Cmbl gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • xenobiotic metabolic process

Cellular Component

Where in the cell the gene product is active
  • extracellular vesicular exosome
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • hydrolase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.