Cenpn Gene Summary [Rat]
Predicted to be involved in CENP-A containing chromatin assembly and chromosome segregation. Predicted to be located in chromosome, centromeric region and nucleus. Predicted to be part of inner kinetochore. Predicted to be active in nucleoplasm. Orthologous to human CENPN (centromere protein N). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cenpn |
| Official Name | centromere protein N [Source:RGD Symbol;Acc:1310953] |
| Ensembl ID | ENSRNOG00000011296 |
| Bio databases IDs | |
| Aliases | centromere protein N |
| Synonyms | 2610510J17Rik, BM039, C16orf60, centromere protein N, Da2-27, Da2-4, ICEN32, RGD1310953 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cenpn often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Kinetochore protein CHL4 like
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- breast cancer
- organismal death
- systemic lupus erythematosus
- nonsyndromic cleft lip and palate
role in cell
- expression in
- proliferation
- apoptosis
- autophagy in
- Gap 0-Gap 1 phase
- cell cycle progression
- paclitaxel resistance
- misalignment
- misalignment in
- metabolism in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cytosol
- nucleoplasm
- kinetochores
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Cenpn gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- chromosome segregation
- CenH3-containing nucleosome assembly at centromere
Cellular Component
Where in the cell the gene product is active
- nucleus
- condensed chromosome inner kinetochore
- cytosol
- nucleoplasm