LOC100909712 Gene Summary [Rat]

Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Predicted to be involved in regulation of RNA splicing. Located in nuclear speck. Orthologous to human CCNL1 (cyclin L1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
LOC100909712
Official Name
cyclin-L1-like [Source:RGD Symbol;Acc:6501887]
Ensembl ID
ENSRNOG00000011586
Bio databases IDs NCBI: 100909712 NCBI: 114121 Ensembl: ENSRNOG00000011586
Aliases cyclin-L1-like
Synonyms 2610030E23Rik, ANIA6A, BM-001, Ccnl, CYCLIN L, cyclin L1, LOC100909712, PRO1073
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Loc100909712 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Cyclin box fold superfamily
  • Cyclin, N-terminal domain
  • protein binding
  • domain present in cyclins, TFIIB and Retinoblastoma

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • breast cancer
  • idiopathic pulmonary fibrosis
regulated by
  • lipopolysaccharide
  • TP53
  • U0126
  • PDGF-BB
  • RB1
  • gentamicin
  • KLF6
  • TBX2
  • niacinamide
  • HuH7 cells
regulates
  • PRKN
role in cell
  • survival
  • mitosis

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoplasm
  • nuclear speckles

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Loc100909712 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • regulation of RNA splicing
  • regulation of apoptotic process
  • regulation of cell cycle
  • regulation of centrosome cycle
  • regulation of transcription from RNA polymerase II promoter

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • nuclear speck
  • cyclin-dependent protein kinase holoenzyme complex

Molecular Function

What the gene product does at the molecular level
  • cyclin-dependent protein kinase regulator activity
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.