CCNL1 Gene Summary [Human]
Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | CCNL1 |
| Official Name | cyclin L1 [Source:HGNC Symbol;Acc:HGNC:20569] |
| Ensembl ID | ENSG00000163660 |
| Bio databases IDs | |
| Aliases | cyclin L1 |
| Synonyms | 2610030E23Rik, ANIA6A, BM-001, Ccnl, CYCLIN L, cyclin L1, LOC100909712, PRO1073 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CCNL1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Cyclin box fold superfamily
- Cyclin, N-terminal domain
- protein binding
- domain present in cyclins, TFIIB and Retinoblastoma
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
- nuclear speckles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CCNL1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of RNA splicing
- regulation of apoptotic process
- regulation of cell cycle
- regulation of centrosome cycle
- regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- nucleus
- nuclear speck
- cyclin-dependent protein kinase holoenzyme complex
Molecular Function
What the gene product does at the molecular level
- cyclin-dependent protein kinase regulator activity
- protein binding