Krt27 Gene Summary [Rat]

Predicted to enable structural molecule activity. Predicted to be involved in epithelial cell differentiation; hair follicle morphogenesis; and intermediate filament organization. Predicted to be located in cytoplasm and intermediate filament. Predicted to be active in cytoskeleton. Orthologous to human KRT27 (keratin 27). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Krt27
Official Name
keratin 27 [Source:RGD Symbol;Acc:1359115]
Ensembl ID
ENSRNOG00000011628
Bio databases IDs NCBI: 450229 Ensembl: ENSRNOG00000011628
Aliases keratin 27
Synonyms CK-27, IRSa3.1, K25IRS3, K27, Ka40, keratin 27, Krt1-c29, KRT25C, mIRSa3.1, stpm
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Krt27 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • SPEC
  • protein binding
  • Intermediate filament protein

Pathways

Biological processes and signaling networks where the Krt27 gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • androgenic alopecia
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Krt27 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • epithelial cell differentiation
  • hair follicle morphogenesis
  • intermediate filament organization

Cellular Component

Where in the cell the gene product is active
  • cytoskeleton
  • extracellular vesicular exosome
  • cytosol
  • intermediate filament

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • structural molecule activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.