B3galnt1 Gene Summary [Rat]
Predicted to enable N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity. Predicted to be involved in protein O-linked glycosylation. Predicted to act upstream of or within oligosaccharide biosynthetic process. Predicted to be active in Golgi membrane. Orthologous to human B3GALNT1 (beta-1,3-N-acetylgalactosaminyltransferase 1 (Globoside blood group)). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | B3galnt1 |
| Official Name | beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) [Source:RGD Symbol;Acc:1304797] |
| Ensembl ID | ENSRNOG00000012019 |
| Bio databases IDs | |
| Aliases | beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) |
| Synonyms | 3-GalNAc-T1, 3-GalTase, B3GALANT1, B3GALT3, b3GT3, beta-1, Beta-1,3-galactosyltransferase, beta-1,3-N-acetylgalactosaminyltransferase 1 (Globoside blood group), beta3Gal-T3, beta-3-Gx-T3, galT3, Gb4Cer, GLCT3, GLOB, Globoside synthase, Mbrn 1, P1, UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 1, UDP-GalNAc:betaGlcNAc β 1,3-galactosaminyltransferase, polypeptide 1, β-1, β-1,3-galactosyltransferase, β-1,3-N-acetylgalactosaminyltransferase 1 (Globoside blood group), β-3-Gx-T3 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat B3galnt1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- UDP-galactose beta-N-acetylglucosamine beta-1,3-galactosyltransferase
- galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase
- galactosyltransferase
- enzyme
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Golgi membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat B3galnt1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein O-linked glycosylation
- oligosaccharide biosynthetic process
- glycosphingolipid biosynthetic process
Cellular Component
Where in the cell the gene product is active
- Golgi membrane
Molecular Function
What the gene product does at the molecular level
- galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity
- UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity